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Index > Protein center > Cd2(Gene name) > Mouse
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  • Cd2 (Gene name),
  • T-cell surface antigen CD2 (Protein name ),  CD2_MOUSE from NCBI database.
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  • General Annotation
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  • Antigen Annotation
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  • Gene name:
    Cd2(Ly-37);
    Protein name:
    T-cell surface antigen CD2;
    Alternative:
    LFA-3 receptor;LFA-2;T-cell surface antigen T11/Leu-5;Lymphocyte antigen 37(Ly-37);
    CD:
    CD2;
    Organism:
    Mouse (Mus musculus). 
    General Annotation
    Sub Unit:
    Interacts with CD2AP and PSTPIP1.
    Function:
    CD2 interacts with lymphocyte function-associated antigen (LFA-3) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.
    Subcellular Location:
    Membrane Single-pass type I membrane protein
    Protein Attributes:
    Sequence length:
    344
    Sequence:
    50:
    MKCKFLGSFF | LLFSLSGKGA | DCRDNETIWG | VLGHGITLNI | PNFQMTDDID | 
    100:
    EVRWVRRGTL | VAEFKRKKPP | FLISETYEVL | ANGSLKIKKP | MMRNDSGTYN | 
    150:
    VMVYGTNGMT | RLEKDLDVRI | LERVSKPMIH | WECPNTTLTC | AVLQGTDFEL | 
    200:
    KLYQGETLLN | SLPQKNMSYQ | WTNLNAPFKC | EAINPVSKES | KMEVVNCPEK | 
    250:
    GLSFYVTVGV | GAGGLLLVLL | VALFIFCICK | RRKRNRRRKD | EELEIKASRT | 
    300:
    STVERGPKPH | STPAAAAQNS | VALQAPPPPG | HHLQTPGHRP | LPPGHRTREH | 
    344:
    QQKKRPPPSG | TQIHQQKGPP | LPRPRVQPKP | PCGSGDGVSL | PPPN
    3D Structure:
    N/A
    Predicted Eptitope:
    Please Sign in.
    EIAab Sequence  Vaild Sequence:
    Please Sign in.
    Related Databases
    SMR:
    KEGG:
    UniGene:
    String:
    Pfam:
    Uniprot:
     
    FOR
    ELISA Kit for Mouse T-cell surface antigen CD2
    Cat.:
    E1576h
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    MSDS:
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    Packing:
    96T
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    ELISA Kit for Mouse T-cell surface antigen CD2
    Cat.:
    E1576r
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    MSDS:
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    96T
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    ELISA Kit for Mouse T-cell surface antigen CD2
    Cat.:
    E1576m
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    MSDS:
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    Packing:
    96T
    CLIA Kit for Mouse T-cell surface antigen CD2
    Cat.:
    U1576r
    Price:
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    MSDS:
    Please sign in first.
    Packing:
    96T
    CLIA Kit for Mouse T-cell surface antigen CD2
    Cat.:
    U1576h
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Range:
    Please sign in first.
    CLIA Kit for Mouse T-cell surface antigen CD2
    Cat.:
    U1576m
    Price:
    Please sign in first.
    MSDS:
    Please sign in first.
    Packing:
    96T
    Polyclonal Antibody for Mouse T-cell surface antigen CD2
    Cat.:
    P1576Rb-m
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse T-cell surface antigen CD2
    Cat.:
    P1576Rb-h
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    Packing:
    40ug/0.2ml
    Polyclonal Antibody for Mouse T-cell surface antigen CD2
    Cat.:
    P1576Rb-r
    Price:
    Please sign in first.
    Packing:
    40ug/0.2ml
    Monoclonal Antibody for Mouse T-cell surface antigen CD2
    Monoclonal Antibody for Mouse T-cell surface antigen CD2
    Monoclonal Antibody for Mouse T-cell surface antigen CD2
    Protein for Mouse T-cell surface antigen CD2
    Protein for Mouse T-cell surface antigen CD2
    Protein for Mouse T-cell surface antigen CD2

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    Precision
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    Recovery
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    Linearity
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    For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.
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    References
    1. 1.
      "The murine homologue of the T lymphocyte CD2 antigen: molecular cloning, chromosome assignment and cell surface expression."
      Sewell W.A. , Brown M.H. , Fink P.J. , Kozak C.A. , Crumpton M.J.
      Eur. J. Immunol.17:1015-1020(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
      strain: B10.A.
    2. 2.
      "Murine and human T11 (CD2) cDNA sequences suggest a common signal transduction mechanism."
      Clayton L.K. , Sayre P.H. , Novotny J. , Reinherz E.L.
      Eur. J. Immunol.17:1367-1370(1987) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    3. 3.
      "Exon-intron organization and sequence comparison of human and murine T11 (CD2) genes."
      Diamond D.J. , Clayton L.K. , Sayre P.H. , Reinherz E.L.
      Proc. Natl. Acad. Sci. U.S.A.85:1615-1619(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA]
      strain: BALB/c.
      tissue: Liver.
    4. 4.
      "Molecular cloning of the murine homologue of CD2. Homology of the molecule to its human counterpart T11."
      Yagita H. , Okumura K. , Nakauchi H.
      J. Immunol.140:1321-1326(1988) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
    5. 5.
      "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
      The MGC Project Team
      Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
      strain: C57BL/6.
      tissue: Hematopoietic.
    6. 6.
      "A novel adaptor protein orchestrates receptor patterning and cytoskeletal polarity in T-cell contacts."
      Dustin M.L. , Olszowy M.W. , Holdorf A.D. , Li J. , Bromley S. , Desai N. , Widder P. , Rosenberger F. , van der Merwe P.A. , Allen P.M. , Shaw A.S.
      Cell94:667-677(1998) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CD2AP
    7. 7.
      "The Wiskott-Aldrich syndrome protein acts downstream of CD2 and the CD2AP and PSTPIP1 adaptors to promote formation of the immunological synapse."
      Badour K. , Zhang J. , Shi F. , McGavin M.K.H. , Rampersad V. , Hardy L.A. , Field D. , Siminovitch K.A.
      Immunity18:141-154(2003) [PubMed] [Europe PMC] [Abstract]
      [15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PSTPIP1
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